NF2 and meningioma: To some extent, Merlin may indirectly regulate modification of FOXM1 protein, which decreases the stability of FOXM1.32 Although the detailed mechanisms underlying the regulation of FOXM1 protein stability by Merlin require further elucidation, this novel finding regarding Merlin/FOXM1/β-catenin signaling is critical to identifying the molecular mechanisms underlying NF2-associated meningioma pathogenesis.