TGFBI has previously been shown highly expressed in mesenchymal subtype glioblastoma and associated with poor prognosis.36 Few reports are available on ADAMTS1 in glioblastoma, but in other cancer types it has been shown to affect several cancer phenotypes, including proliferation.37 Of note, it is also of importance to investigate the effects of the different secretomes on neighboring non-neoplastic cells, which has not been addressed in this work. This evidence concerns the gene ADAMTS1 and cancer.