The median rCBV values for IDH-mutant astrocytoma were also lower for those with the presence of a T2/FLAIR-mismatch sign (median rCBV of 1.22 [IQR, 1.03–1.32]) as compared to those without a T2/FLAIR-mismatch sign (median rCBV of 1.52 [IQR, 1.24–1.97]), although the difference did not reach statistical significance (P = .0757; Figure 4, bottom row). The gene discussed is IDH1; the disease is astrocytoma (excluding glioblastoma).