FGFR3 and Camptodactyly - tall stature - scoliosis - hearing loss: Since there are no studies dissecting the role of Wnt signaling in the skeleton maldevelopment resulting from FGFR3 deletion, our results for the first time reveal that fgfr3 deficiency upregulates the Wnt/β-catenin pathway, which may be involved in the pathogenesis of the abnormal skeleton phenotype in CATSHL syndrome.