KMT2A and Kabuki syndrome: Interestingly, five more patients carrying KMT2A variants were clinically diagnosed with Coffin–Siris syndrome (CSS, OMIM #135900, #614608, #614607, #614609, #616938, #615866, #617808, #618362, #618027, #618506) (pt #K2431) [20], Cornelia de Lange syndrome (CdLS, OMIM #122470, #300590, #610759, #614701, #300882) (pt CdLs #3 and pt #1) [21, 22], Kabuki syndrome (KS, OMIM #147920, #300867) (pts #KS8-KS29) [23], and Rubinstein–Taybi syndrome (RSTS, OMIM #180849, #613684) (pt #103) [24] respectively (Supplementary Table S1).