AKT1 and cancer: Functional enrichment analysis showed that these DGEs were significantly enriched in biological processes including extracellular matrix (ECM) organization, response to estradiol, collagen fibril organization, negative regulation of cell proliferation, cell adhesion, blood vessel development, positive regulation of epidermal cell differentiation/apoptotic process, cell migration, etc.; KEGG pathways include focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, and pathways in cancer.