Increased TyG index (per 1-unit) was consistently related to primary endpoint in various subgroups, including age ≤ 65 or > 65 years, female or male, BMI ≤ 28 or > 28 kg/m2, with or without hypertension, UA or NSTEMI, HbA1c ≤ 7 or > 7%, LDL-C ≤ 70 or > 70 mg/dL, with or without pre-admission medication including statins, oral hypoglycemic agents and insulin (Fig. 3). This evidence concerns the gene INS and Hypertension.