When compiling all the expression and RFS data, we could sub-classify genes with high expression in PCa vs. normal gland or normal adjacent to tumor tissue and significantly decreased RFS (RCC1 and PCDC5) or with low expression in PCa and decreased RFS (ASPH, GSN, HSPB1, SQSTM1, ANXA2, MX1, and PURA) (Table 2, white dots). The gene discussed is HSPB1; the disease is posterior cortical atrophy.