All SEMA3 receptors, except PLXNA1 which showed negligible positive correlation, were negatively correlated with RNAss score with varying degrees (correlation coefficients r: −0.65 to −0.13) (p < 0.0001), where NRPs showed the strongest association (r = −0.65 and −0.48 for NRP1 and NRP2, respectively) across cancer types. Here, PLXNA1 is linked to cancer.