Furthermore, by analyzing the disease-free survival data in the TCGA cancer database, we ascertained that high expression of Ki67 was associated with significantly reduced disease-free survival, and that a low SERPINB5, together with a high BIRC5 transcript expression—indicative of an activated NFκB pathway—was associated with even lower survival rates (Figure 5C). The gene discussed is SERPINB5; the disease is cancer.