ACE and diabetes mellitus: In the adjusted Cox model including age, gender, season, presence of multivessel disease, previous coronary events/revascularization, C-reactive protein (CRP), glomerular filtration rate, LV ejection fraction, treatment with ACE-inhibitors/ARBs and beta blockers, both DM (HR 1.3, 95% CI 1.05–1.61, p = 0.014) and VitD deficiency (HR 1.3, 95% CI 1.04–1.64, p = 0.022) remained independently associated with the composite end-point (Table 2).