Another HIF-1α-suppressing lncRNA was identified by Xiang and coworkers [37], who found that c-Myc mediated suppression of lncRNA isocitrate dehydrogenase 1 antisense RNA 1 (IDH1-AS1) in cancer cell lines activates HIF-1α-induced glycolysis under normoxic conditions. The gene discussed is MYC; the disease is cancer.