In this study, we also showed that expressing Glo1 one week after the onset of T1DM, blunted the formation of the MG-H1 adduct on Ca2+ cycling (RyR2, SERCA2, MHC-α/β, Na+, K+-ATPase, and Kv 4.2/4.3) and mitochondria (NDUFV3 and NDUFV10) proteins. This evidence concerns the gene RYR2 and type 1 diabetes mellitus.