Particularly, a cross-sectional study involving 46 patients aged 55 to 80 years (mean 71.1 ± 6.7 years, 36 men, 15 patients with type 2 diabetes mellitus) explored sclerostin production in atherosclerotic plaques of patients who underwent carotid endarterectomy. Here, SOST is linked to type 2 diabetes mellitus.