More recently, researchers reported that a genetically low determination of Lp (a) levels reduces the risk of CAVD by approximately 37% [124] and that patients with elevated plasma Lp (a) levels and phospholipids, oxidized in apolipoprotein B (OxPl-apoB), have a greater propensity for the development of aortic stenosis [121]. This evidence concerns the gene APOB and congenital bilateral aplasia of vas deferens from CFTR mutation.