TLR8 and infection: Two small pathways (first: LAMP-TLR2/TLR6-MyD88-MKK6-AP1-IL1B; second: LAMP-TLR8-MyD88-IRF5-RANTES) were identified using the KEGG database, indicating that DEGs related with MO infection were mapped to the TLR signaling pathway (Fig 3).