The most molecular function (MF) terms were “binding, protein binding, catalytic activity, ion binding, and metal ion binding ” at 7 d after MCAO (Figure 4A), and then shifted to following predominance of “small GTPase binding, Ras GTPase binding, protein serine/threonine kinase activity, GTPase activator activity, and GTPase regulator activity” at 14 d after stroke (Figure 4B). The gene discussed is AKT1; the disease is Stroke.