Allele rs2476601 T was observed at thefrequency of about 14% in both the patient and control samples (Lobo-Alves et al., 2019a).So, variants in structural and regulatory sites of PTPN22 andits flanking regions are not susceptibility factors for pemphigus, and it seemssettled that the genetic variation of LYP has no impact on pemphigus diseasesusceptibility. Here, PTPN22 is linked to pemphigus.