Since the SARS‐CoV‐2 infected patients with certain common chronic diseases also face a relatively high risk of poor clinical outcomes,2, 3, 4, 5 we further explored the underlying mechanism by profiling ACE2 expression with the expression data of common chronic diseases regarding angiocardiopathy, type 2 diabetes (T2D), liver, hypertension and pneumonia obtained from GEO.11 The gene discussed is ACE2; the disease is hypertensive disorder.