Mutations or INDELs in 50 genes (PDE4DIP, NOTCH2, FANCA, BCR, CLTCL1, MYH11, NOTCH1, COL1A1, CAMTA1, ALK, NIN, CIITA, CARD11, RECQL4, USP6, NF1, NUP214, KIAA1549, MYH9, FLT3, NSD1, PCSK7, XPC, PMS2, SETBP1, SRGAP3, ASXL1, PDGFRA, ATIC, RALGDS, PRDM16, TSHR, FGFR2, EGFR, CDH11, DNM2, SYK, MUTYH, BCOR, FNBP1, RAC1, IL7R, CNOT3, RNF43, TP53, KCNJ5, MEN1, SH2B3, SRSF2, CREB3L1) were shared across all patients with leukemia. The gene discussed is BCOR; the disease is leukemia.