Mutations or INDELs in 50 genes (PDE4DIP, NOTCH2, FANCA, BCR, CLTCL1, MYH11, NOTCH1, COL1A1, CAMTA1, ALK, NIN, CIITA, CARD11, RECQL4, USP6, NF1, NUP214, KIAA1549, MYH9, FLT3, NSD1, PCSK7, XPC, PMS2, SETBP1, SRGAP3, ASXL1, PDGFRA, ATIC, RALGDS, PRDM16, TSHR, FGFR2, EGFR, CDH11, DNM2, SYK, MUTYH, BCOR, FNBP1, RAC1, IL7R, CNOT3, RNF43, TP53, KCNJ5, MEN1, SH2B3, SRSF2, CREB3L1) were shared across all patients with leukemia. The gene discussed is SRGAP3; the disease is leukemia.