Mutations or INDELs in 50 genes (PDE4DIP, NOTCH2, FANCA, BCR, CLTCL1, MYH11, NOTCH1, COL1A1, CAMTA1, ALK, NIN, CIITA, CARD11, RECQL4, USP6, NF1, NUP214, KIAA1549, MYH9, FLT3, NSD1, PCSK7, XPC, PMS2, SETBP1, SRGAP3, ASXL1, PDGFRA, ATIC, RALGDS, PRDM16, TSHR, FGFR2, EGFR, CDH11, DNM2, SYK, MUTYH, BCOR, FNBP1, RAC1, IL7R, CNOT3, RNF43, TP53, KCNJ5, MEN1, SH2B3, SRSF2, CREB3L1) were shared across all patients with leukemia. Here, CNOT3 is linked to leukemia.