S100A8 and cardiovascular disorder: For the top 20 FDEGs, six genes, namely natriuretic peptide A (NPPA), natriuretic peptide B (NPPB), Ficolin 3 (FCN3), phospholipase A2 group IIA (PLA2G2A), S100 calcium binding protein A8 (S100A8) and frizzled‐related protein (FRZB), were already shown to play important roles in HF or cardiovascular disease.