BRCA2 and breast carcinoma: BRCA1 and BRCA2 mutations have also been reported in CVDs, for example, mutations in BRCA1 and BRCA2 are shown to be associated with a two‐fold increased risk for diabetes (Bordeleau et al., 2011) and a 37% increase of all‐cause mortality risk for breast cancer patients mainly due to CVDs (Zhou, Zhang, Gu, & Xia, 2015).