BRCA1 and endothelial dysfunction: Moreover, lipid and metabolite deregulation is observed in humans carrying either BRCA1 or BRCA2 (BRCA1/2) mutations and a genetic analysis identified BRCA2 SNPs’ association with plasma‐lipid levels (Ramadan et al., 2015; Stanwell & Gluch, 2015), which plays an important role in endothelial dysfunction and atherosclerosis (Asselbergs et al., 2012).