ANGPTL4 expression was evaluated in multiple organs from AP and SAP mice, and it progressively increased in the pancreas according to the severity of pancreatitis compared with that of other organs; and in normal mice, ANGPTL4 expression was lower in pancreatic tissues than in adipose, muscle, heart, liver, or kidney tissues (Appendix Fig S1C). The gene discussed is ANGPTL4; the disease is alkaline phosphatase measurement.