TNF and rheumatoid arthritis: According to the Finnish ROB-FIN register study, in 2004–14 the first TNF-inhibitors were initiated to RA patients after a median (IQR) of 8.2 (2.4–17) years of disease duration, most often with adalimumab (39%) or etanercept (39%), while infliximab was a rarer choice (12%) [33].