Among them, it was found that there was a highly conserved miR-185 responsive element in the 3'-untranslated region (3'-UTR) of VEGF-A and PDGF. It has been reported that VEGF-A is an important angiogenesis regulator that is highly expressed in tumor tissues such as endometrial tissue, and it is proposed that it is closely associated with aggressive tumor features (12, 13). This evidence concerns the gene VEGFA and neoplasm.