In order to examine factors involved in cisplatin resistance of ESCC, we measured the expression levels of 7 genes (IL-1β, IL-6, IL-8, IL-11, IL-32, HGF, and CXCL1) that were reported to be secreted from CAFs in activated fibroblasts and NFs. The gene discussed is IL11; the disease is esophageal squamous cell carcinoma.