As diffuse GC is classified as infiltrative-type GC in Ming’s classification, this strategy ensures that the subsequent candidate genes (COL4A1, COL3A1, and COL1A2) and Ming’s classification-related miR-29b/c are all associated with the same GC phenotype, which has the same morphological performance in clinical pathology. This evidence concerns the gene COL3A1 and gastric cancer.