Similar results were also obtained in a mouse model of breast cancer in which transplanted human MSCs significantly reduced CD3+ NKp46 NKT-like cells, increased CD4+ Foxp3 T cells and IL-10 expressing CD4+ cells, increased serum Th2 cytokines, and decreased serum Th1 cytokines (Ljujic et al., 2013). Here, CD4 is linked to breast carcinoma.