Based on the outcome of in vitro and in vivo studies, it is thought that RV may enhance Th2 cytokines via the expression of TSLP and IL-25 derived from airway epithelial cells; thus, exacerbating the lung disease in patients with asthma (Kato et al., 2007; Uller et al., 2010; Han et al., 2017). The gene discussed is IL25; the disease is asthma.