Immunohistochemical staining of tumor cells (III-1 and II-2) demonstrated moderate positivity for MLH1 (Figures 2A,I) and PMS2 (Figures 2C,K) proteins, weak positivity for MSH6 (Figures 2D,L), and lack of expression of MSH2 protein (Figures 2B,J). This evidence concerns the gene MSH6 and neoplasm.