NPM1 and anaplastic large cell lymphoma: Although NPM1/ALK fusion transcripts are the most common rearrangements in ALK+ ALCL, other rearrangements, such as TPM3 (1q25), ATIC (2q35), TFG (3q21), TPM4 (19p13.1), MYH9 (22q11.2), RNF213 (17q25), TRAF1 (9q33.2), CLTC (17q23), and MSN (Xq11), have also been reported (54).