We found that TFs associated with stemness (e.g., MEF2, AP1, SOX9, GATA3, and GFI1) or leukemogenesis (CEBPA and BACH1) were significantly enriched for DEGs between SH3TC2 high-expression and SH3TC2 low-expression group, suggesting that these TFs may be potential targets of SH3TC2 in AML (Figure 10). This evidence concerns the gene BACH1 and acute myeloid leukemia.