To investigate the nature of CEACAM 5 (CEA) and 6 variants expressed on tumor cells, we performed whole exome sequencing of OV90 (NEO-201pos), LS174T (NEO-201pos), SW480 (NEO-201neg), and OVCAR8 (NEO-201neg) cell lines. The gene discussed is CEACAM5; the disease is neoplasm.