IDO1 and neoplasm: To determine the extent to which indoximod modulates IDO expression in dendritic cells, we examined IDO expression by dendritic cells from the tumor draining lymph nodes of mice bearing established B16F10 tumors treated with an immunotherapy consisting of the adoptive transfer of tumor-specific pmel-1 T cells and gp100 peptide vaccination (per the experimental design outlined in Figure 2A).