NFKB1 and colorectal cancer: Among the canonical pathways predicted to be deactivated were colorectal cancer metastasis signaling (Z-score = −1.5), NF-kB signaling (Z-score = −1.604), B cell receptor signaling (Z-score = −1), dendritic cell maturation (Z-score = −0.905), and the Th1 pathway (Z-score = −0.378) (Figure 9A bottom).