HOTAIR and glioblastoma: Pathway analysis using IPA revealed relatively few significant pathways including HOTAIR regulatory pathway (Z-score = 1.134), colorectal cancer metastasis signaling (Z-score = 0.378), neuroinflammation signaling pathway (Z-score = −1.134), and glioblastoma multiforme signaling (Z-score = −0.447) (Figure 4A bottom).