Although no significant association was observed between Scinderin expression level and GC grade, the mean Gelsolin expression showed a significant difference between grade II (0.25 ± 0.26) and III (1.01 ± 1.29) (p =0.05) as well as grade I (0.25 ± 0.26) and IV (1.84 ± 3.23) (p=0.04). The gene discussed is SCIN; the disease is gastric cancer.