In this study, the authors sought to create new molecules that presented similar characteristics to the structure of 1,2-NQ, since in the condition of type 2 diabetes, inhibition of PTP1B could be a new therapeutic target for the treatment of this disease (Ahn et al., 2002[3]; Cheon et al., 2004[9]). Here, PTPN1 is linked to type 2 diabetes mellitus.