IL17A and infection: The notion that IL-17A is required for development of a type-2 response appears counter to the evidence that type-2 cytokines suppress IL-17A production.9,10 However, previous studies using murine models of allergic inflammation also show impaired type-2 immunity in the face of IL-17A-deficiency12,13 or blockade.14 In an infection or injury context, the specific tissue as well as timing might all play decisive roles in whether IL-17A augments or suppresses type-2 responses.