IL17A and fungal infectious disease: IL-17A, the key cytokine of the IL-17 family, is central to barrier immunity, combating fungal infections and inducing antimicrobial proteins as well as neutrophil activating and recruiting chemokines.2 However, in the context of type-2 immunity, a combination of type-2 cytokines and IL-17A is often a signature for severe disease pathology.