ALDOC and neoplasm: Genes correlated with lncRNAs that are uniquely associated with tumor grade in the glucose pathway that are down-regulated include ALDOB and ALDOC (Table S1a, boxed in orange) which are glycolytic adolase enzyme isoforms that cleaves Fructose 1,6-biphosphate to produce Dihydroxyacetone phosphate and Glyceraldehyde 3-phosphate63.