NSD2 and B-cell chronic lymphocytic leukemia: As previously described, the most common Ig translocation in CLL was the t(14;18) [IGH-BCL2] in seven cases; the t(11;14) [CCND1-IGH, n = 62] or t(2;11) [IGK-CCND1, n = 1] in all but one MCL (note that this later case had the characteristics of a CyclinD1-negative MCL);34 the t(11;14) [CCND1-IGH, n = 7], MYC-IG (n = 4), and t(4;14) [NSD2-IGH, n = 2] in MM; and the t(14;18) [IGH-BCL2, n = 22] and t(3;14) [BCL6-IGH, n = 5] in DLBCL (Fig. 3e).