IL1B and Sepsis: Intraperitoneal administration of 5-MTP to LPS-induced sepsis model results in suppression of macrophage activation and cytokine expression accompanied by reduction of serum cytokines (IL-6, IL-1β, TNFα and IFNγ) and chemokines (CXCL-1, MCP-1, Rantes and Eotaxin) [3].