KCNH4 and small cell lung carcinoma: However, in the case of small-cell LC (SCLC) patients, although a small clinical trial suggested longer survival and relapse-free survival in patients treated with an immunoadjuvant consisting of BCG extract bound to hydroxyapatite and microparticulated tuberculin called CalTUMP in combination with BEC2 (which is an anti-idiotypic antibody mimicking the GD3 ganglioside expressed on most SCLC cells) [96], two other studies demonstrated no beneficial effect of the combined therapy [97,98].