Regarding, VAP resolution, Povoa et al. [33] aimed to analyse the kinetic performance of several biomarkers (C-reactive protein (CRP), procalcitonin (PCT), and the mid-region fragment of pro-adrenomedullin (MR-proADM)) in a prospective, multicenter, observational study of microbiologically documented VAP. This evidence concerns the gene CRP and ventilator-associated pneumonia.