CD81 and Alzheimer disease: In a model including all EV types and terms for Group and Group*EV type interaction, NEVs of AD participants produced a significant MTT decrease (AD vs. Normal, p = 0.003), and so did AEVs (AD vs. Normal, p = 0.006), but CD81+EVs did not (AD vs. Normal, p = 0.904) and neither did total EVs (AD vs. Normal, p = 0.675).