The patients with diffuse PD-L1 tumor cell expression had a worse prognosis than those with marginal PD-L1 expression (hazard ratio (HR) 3.055, p = 0.004), and those with marginal or negative PD-L1 expression (HR 2.067, p = 0.023), as shown in Figure 3b. This evidence concerns the gene CD274 and neoplasm.