Both CDs impacted cancer-related pathways (e.g., Colorectal cancer, Pancreatic cancer, Endometrial cancer), as well as other pathways associated with tumorigenesis (e.g., Wnt signaling pathway, Ras signaling pathway, ErbB signaling pathway), immune response-related processes (T cell receptor signaling pathway, Fc gamma R-mediated phagocytosis) and cell-extracellular matrix (ECM) interactions (Mucin type O-Glycan biosynthesis). The gene discussed is EGFR; the disease is familial pancreatic carcinoma.