As we know glycolysis enzyme could act nuclear function to regulate transcription of gene acting in cell cycle, such as GADPH [30], so we carried out correlation analysis of mRNA expression between GAPDH and cell cycle-related genes TUBA1C, TUBA1B, CCNB1 and the results showed that GAPDH was positively correlated with them in 24~25 cancer types (Figure 5e, p < 0.05). The gene discussed is CCNB1; the disease is cancer.