T-complex protein 1 ring complex (TRiC; also known as chaperonin containing TCP1 complex, CCT) protein subunits, CCT2, CCT3, CCT4, CCT5, CCT7 and TCP1 were measured in high levels (FC ≥ 2) in plasma-EVs from GBM patients relative to the controls, with significant increases detected for CCT2 and CCT7 (adj. This evidence concerns the gene CCT5 and glioblastoma.