They further identified four immune-regulatory hub genes: RAS protein activator-like 3 (RASAL3), protein tyrosine phosphatase, receptor type C (PTPRC), inositol polyphosphate-5-phophatase D (INPP5D), and SAM and SH3 domain-containing 3 (SASH3) that were associated with diverticulitis [25]. Here, SASH3 is linked to Colonic diverticula.