In addition to known inflammatory cytokines, SUDD patients also showed increased expression of tissue inflammatory markers including the basic fibroblast growth factor (b-FGF) and sydecan-1 (SD1) [19], as well as significant upregulation of the neuropeptide neurokinin 1 (NK1) [17], compared to patients with diverticulosis. The gene discussed is FGF2; the disease is diverticular disease.