Moreover, the negative correlation between TAC in NWS and SWS and the serum concentration of anti-TPO as well as between GSH and IL-1β concentrations in SWS confirm that the exhaustion of antioxidant sources in salivary glands is related to an elevated oxidative stress level due to autoimmunity-related inflammation and that increased concentration of autoimmune antibodies is a key factor for the enhancement of ROS production. This evidence concerns the gene TPO and Autoimmunity.